Post-transplant cholangiopathy: Classification, pathogenesis, and preventive strategies

Pathogenesis and Preventive Strategies of Chronic Dysfunction of Renal Allograft

An update on necrotizing enterocolitis: pathogenesis and preventive strategies

Necrotizing enterocolitis (NEC) is one of the most critical morbidities in preterm infants. The incidence of NEC is 7% in very-low-birth-weight infants, and its mortality is 15 to 30%. Infants who survive NEC have various complications, such as nosocomial infection, malnutrition, growth failure, bronchopulmonary dysplasia, retinopathy of prematurity, and neurodevelopmental delays. The most impo...

Portal cholangiopathy: radiological classification and natural history.

BACKGROUND/AIM Portal cholangiopathy (PC) is identified in over 80% of patients with portal vein thrombosis (PVT), but the true impact of this condition is not well known. This study investigated the relationship between cholangiographic abnormalities and clinical symptoms and their evolution over time. PATIENTS/METHODS 67 consecutive patients with non-tumoral non-cirrhotic PVT following a st...

post-transplant anemia: treatable multifactorial pathogenesis and negative impact on graft and possibly patient survival

Innate immunity in the pathogenesis of cholangiopathy: a recent update.

Biliary innate immunity is involved in the pathogenesis of cholangiopathies in patients with various biliary diseases. Biliary epithelial cells possess an innate immune system consisting of the Toll-like receptor (TLR) family and recognize pathogen-associated molecular patterns (PAMPs). Recently, regulatory mechanisms by intracellular negative regulators including peroxisome proliferator-activa...